Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Gymnemagenin United States Pharmacopeia (USP) Reference Standard | 22467-07-8 | MFCD06656306 | 15MG
Gymnemagenin United States Pharmacopeia (USP) Reference Standard | Mol Wt: 506.71 | 22467-07-8 | MFCD06656306 | 15MG
Apexbio Technology LLC Milrinone 78415-72-2 100mg
Milrinone (CAS 78415-72-2) is a selective inhibitor of phosphodiesterase 3 (PDE3) demonstrating an IC50 of 56 12 nM for PDE3 inhibition It acts on both PDE3A localized predominantly in cardiac tissue vascular smooth muscle and platelets and PDE3B found in adipose tissue liver and pancreatic islets Milrinone increases intracellular cAMP levels in platelets with an EC50 of 5329 970 nM leading to enhanced contractility and vasodilation effects This profile supports its utility in cardiovascular research and metabolic studies involving cAMP-mediated signaling pathways
Apexbio Technology LLC Dibucaine (Cinchocaine) HCl 61-12-1 5g
Dibucaine (Cinchocaine) HCl (CAS 61-12-1) is a synthetic amide-type local anesthetic widely used in biomedical research It acts by reversibly binding to and inhibiting voltage-gated sodium channels in neuronal membranes thereby suppressing the initiation and propagation of nerve impulses Through this mechanism dibucaine impedes sensory signal transmission making it a valuable tool for investigating ion channel function neuronal excitability and pathways underlying pain perception Its application extends to in vitro studies of nerve conduction and as a reference compound in anesthetic pharmacology
Medchemexpress LLC Risperidone | 106266-06-2 | MFCD00274576 | 99.9% | 410.48 g·mol⁻¹ | C23H27FN4O2 | 5 MG
Risperidone is an antipsychotic research compound used in laboratory and analytical applications. It functions as a serotonin 5-HT2A receptor blocker, a P-glycoprotein inhibitor, and a potent dopamine D2 receptor antagonist, and is provided as a high-purity reference material for in vitro studies.
- Acts as a 5-HT2A receptor blocker and dopamine D2 antagonist.
- Demonstrated high binding affinity (Ki ≈ 4.8-5.9 nM for 5-HT2A and D2).
- Supplied in small research quantities suitable for assay development.
- High chemical purity appropriate for analytical work (purity 99.87% by HPLC).
- Molecular formula C23H27FN4O2; molecular weight 410.48 g·mol⁻¹.
![eMolecules 1279031-70-7 | Rosuvastatin-d3 (sodium) | Medchem Express | MFCD08460959 | 506.540 | C22H27FN3NaO6S | 98.000 | [Na+].[2H]C([2H])([2H])N(c1nc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(n1)-c1ccc(F)cc1)S(C)(=O)=O | 1mg | 415687929](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502503057.JPG-250.jpg)
eMolecules 1279031-70-7 | Rosuvastatin-d3 (sodium) | Medchem Express | MFCD08460959 | 506.540 | C22H27FN3NaO6S | 98.000 | [Na+].[2H]C([2H])([2H])N(c1nc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(n1)-c1ccc(F)cc1)S(C)(=O)=O | 1mg | 415687929
Rosuvastatin-d3 (sodium) | Medchem Express | 1279031-70-7 | MFCD08460959 | 506.540 | C22H27FN3NaO6S | 98.000 | [Na+].[2H]C([2H])([2H])N(c1nc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(n1)-c1ccc(F)cc1)S(C)(=O)=O | 1mg | 415687929
Medchemexpress LLC Fluvoxamine maleate | 61718-82-9 | 99.8% | C19H25F3N2O6 | 10 MM * 1 ML
Fluvoxamine maleate is an antidepressant that functions pharmacologically as a selective serotonin reuptake inhibitor. It is effective in inhibiting 5-HT uptake by blood platelets and brain synaptosomes. It appears to improve combat-related PTSD symptoms, although findings are limited by high attrition rates and the absence of a placebo group in some studies.
- Functions as a selective serotonin reuptake inhibitor
- Effective in inhibiting 5-HT uptake by blood platelets and brain synaptosomes
- Antagonizes reserpine-induced lowering of pentamethylenetetrazole convulsive threshold
- Does not produce stimulatory effects in rats when rapidly acting reserpine-like compounds are administered after a dose
- Potency in reducing ethanol-maintained behavior varies depending on whether ethanol is available in isolation or concurrently with food
TARGETMOL CHEMICALS INC Atovaquone 50MG
Also available in 1 mL, 10 mg, 25 mg, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Atovaquone (Atavaquone) is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols. Purity 99.53%
Apexbio Technology LLC Fenticonazole Nitrate 73151-29-8 10mg
Fenticonazole Nitrate (CAS 73151-29-8) is a small-molecule inhibitor targeting fungal cytochrome P450 enzyme CYP51A1 (lanosterol 14 -demethylase) It is designed to inhibit the demethylation step required for ergosterol biosynthesis thereby disrupting fungal cell membrane integrity and growth Fenticonazole Nitrate exerts its biological activity primarily through inhibition of CYP51A1 In experimental studies Fenticonazole Nitrate demonstrates inhibitory activity with reported IC50 values for CYP51 inhibition typically in the low micromolar concentration in fungal models such as Malassezia furfur and Candida albicans Based on these pharmacological properties Fenticonazole Nitrate holds research potential in antifungal modes of action studies and antifungal screening assays
Apexbio Technology LLC Cefetamet pivoxil hydrochloride 111696-23-2 25mg
Cefetamet pivoxil hydrochloride (CAS 111696-23-2) is a third-generation cephalosporin antibiotic targeting penicillin-binding proteins It is designed to inhibit these enzymes thereby disrupting bacterial cell wall biosynthesis in Gram-positive and Gram-negative bacteria Cefetamet pivoxil hydrochloride exerts its biological activity primarily through inhibition of peptidoglycan synthesis In in vitro antibacterial assays cefetamet pivoxil hydrochloride demonstrates inhibitory activity with IC50 values within the micromolar range in clinical isolates associated with respiratory and urinary infections Based on these pharmacological properties cefetamet pivoxil hydrochloride holds research potential in studies of bacterial enzyme inhibition antibiotic resistance mechanisms and antimicrobial susceptibility profiling
TARGETMOL CHEMICALS INC Magnolol 100MG
Also available in 1 g, 1 mL, 10 mg, 25 mg, 50 mg, 500 mg and bulk. Please contact Fisher for quotes. Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRalpha( EC50=10.4 uM) and PPARgamma(EC50=17.7 uM). It blocks TNF-alpha-induced NF-KB activation. Purity 100%
Sigma Aldrich Fine Chemicals Biosciences alpha-Tocopherol British Pharmacopoeia (BP) Reference Standard | 10191-41-0 | MFCD00006848 |
alpha-Tocopherol British Pharmacopoeia (BP) Reference Standard | Mol Wt: 430.71 | 10191-41-0 | MFCD00006848 |
Sigma Aldrich Fine Chemicals Biosciences Amlodipine besylate >=98% (HPLC) | 111470-99-6 | MFCD00887594 | 10MG
Amlodipine besylate >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 567.05 | 111470-99-6 | MFCD00887594 | 10MG
Apexbio Technology LLC Metoclopramide 364-62-5 500mg
Metoclopramide (CAS 364-62-5) is a small molecule that primarily acts as an antagonist at dopamine D2 receptors and also exhibits mixed activity as a 5-HT3 receptor antagonist and 5-HT4 receptor agonist Through inhibition of D2 dopaminergic signaling it enhances gastrointestinal motility and exerts antiemetic effects Metoclopramide has been extensively investigated for applications in managing gastrointestinal disorders such as gastroparesis and gastroesophageal reflux disease as well as for alleviating nausea and vomiting including in pregnant women Research supports the safety profile of this compound for fetal outcomes when administered during pregnancy reinforcing its utility in reproductive and gastrointestinal pharmacology studies